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姓名 連剛逸
年級 已畢業學長
組別 己組、基因體國家型計畫
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學歷
    國立成功大學 工程科學系 學士(2001-2004) 國立成功大學 奈米科技暨微系統工程研究所 碩士(2005-2006) 國立成功大學 奈米科技暨微系統工程研究所 博士(2007-2009)
經歷
    中國工程師學會 成大分會 工業參觀 中國工程師學會 成大分會 專題演講 南區遠哲科學趣味競賽 評審 成功大學工科系 92級送舊晚會 主持人 成功大學工科系 92級畢業典禮 在校生代表 成功大學工科系暨台南師範學院音教系 96級迎新宿營 行政長 國立成功大學 工程科學系 94級 學藝股長 國立成功大學 工程科學系 94級 系學會 文書部長 課程與教學季刊(Curriculum & Instruction Quarterly, TSSCI) 助理編輯 (2005.7-2007.1) 中華民國力學學會會員 現職:台積電工程師
專長及研究領域
    數位式微流體驅動(Digital Microfluids System, EWOD) 聚合酶連鎖反應(Polymerase Chain Reaction , PCR) 微型磁珠(Magnetic Bead) 微型磁力元件(Micro electromagnet) 微流體控制系統(Microfluidic systems) 8051微處理器控制元件(8051 microprocesser components)
榮譽及獎勵
    2004中工會93學年度成大全校學生論文比賽電機資訊組第一名 2004中工會93學年度全國學生論文比賽電機資訊組優等 2005第30屆全國力學會議第九屆學生論文競賽熱流能源組佳作 2006高雄市電腦公會95學年度優秀研究生獎學金 2007第二屆龍騰微笑競賽一般組佳作 2007第五屆國家新創獎學生研究組第二名 2008第六屆國家新創獎學術研究組獲獎 2009第一屆成功大學校園創業競賽銅牌獎 2009財團法人中技社98年度科技研究獎學金
專利
    A. Patents: 1. “聚合酶連鎖反應晶片,” 發明人: 李國賓,連剛逸,中華民國發明專利第I319012號, 2010/01/01~2025/11/21. 2. “整合型生物晶片,” 發明人:李國賓,黎煥耀,連剛逸,李婉綺, 中華民國發明專利第I319434號, 2010/01/11~2026/01/11. 3. “可快速偵測之生醫微流體晶片,” 發明人:李國賓,楊松益,連剛逸,黎煥耀,黃國珍, 中華民國發明專利第200912310號, 專利公開日2009/03/16. 4. “用於快速純化萃取生物分子之生物晶片,” 發明人:李國賓,連剛逸,劉倩如, 中華民國發明專利第200925593號, 專利公開日2009/06/16. 5. “生物晶片,” 發明人:李國賓,連剛逸,劉倩如, 中華民國發明專利第200932916號, 專利公開日2009/08/01. 6. “免疫分析晶片,” 發明人:李國賓,黎煥耀,李侑芳,連剛逸, filing date: 2009/3/20 with a filing number 98109045. 7. “用以合成磁性微粒的方法及微流體晶片,” 發明人:李國賓,李珍儀,連剛逸, filing date: 2009/5/27 with a filing number 98117735. 8. “微流體晶片,” 李國賓、楊松益、連剛逸、翁振勛, filing date: 2009/10/30 with a filing number 98136932. 9. “Immunoassay Biochip” 發明人:李國賓、黎煥耀、李侑芳、連剛逸, patent file to USPTO on 2010/03/09 with a filing number 12/659,422. 10. “Microfluidic chip” 發明人:李國賓、楊松益、連剛逸、翁振勛, patent file to USPTO on 2010/06/07 with a filing number 12/795,445. B. Journal Papers: 1. Jr-Lung Lin, Gwo-Bin Lee, Yi-Hsien Chang and Kang-Yi Lien, “Model Description of Contact Angles in Electrowetting on Dielectric Layers,” Langmuir, 22(1), 484-489, 2006. (SCI; Impact factor= 4.097) 2. Kang-Yi Lien, Wan-Chi Lee, Huan-Yao Lei, and Gwo-Bin Lee, “Micro Reverse Transcription Polymerase Chain Reaction Systems Using Super-paramagnetic Beads for Virus Detection,” IEEE Review on Advances of Micro, Nano, and Molecular Systems, 1, 309-310, 2006.(SCI) 3. Kang-Yi Lien, Wan-Chi Lee, Huan-Yao Lei and Gwo-Bin Lee, “Integrated Reverse Transcription Polymerase Chain Reaction Systems for Virus Detection,” Biosensors and Bioelectronics, 22(8), 1739-1748, 2007. (SCI; Impact factor= 5.143) 4. Kang-Yi Lien, Jr-Lung Lin, Cheng-Yu Liu , Huan-Yao Lei and Gwo-Bin Lee, “Purification and Enrichment of Virus Samples Utilizing Magnetic Beads on a Microfluidic System,” Lab on a Chip, 7(7), 868-875, 2007. (SCI; Impact factor= 6.478) 5. Wan-Chi Lee, Kang-Yi Lien, Gwo-Bin Lee and Huan-Yao Lei, “An Integrated Microfluidic System Using Magnetic Beads for Virus Detection,” Diagnostic Microbiology and Infectious Disease, 60(1), 51-58, 2008. (SCI; Impact factor= 2.139) 6. Kang-Yi Lien, Wang-Ying Lin, Yu-Fang Lee, Chih-Hao Wang, Huan-Yao Lei and Gwo-Bin Lee, “Microfluidic System Integrated with Sample Pretreatment Device for Fast Nucleic Acid Amplification,” IEEE/ASME Journal of Microelectromechanical Systems, 17(2), 288-301, 2008. (SCI; Impact factor= 2.226) 7. Sung-Yi Yang, Kang-Yi Lien, Kao-Jean Huang, Huan-Yao Lei and Gwo-Bin Lee “Micro Flow Cytometry Utilizing a Magnetic Bead-based Immunoassay for Rapid Virus Detection,” Biosensors and Bioelectronics, 24(4), 861-868, 2008. (SCI; Impact factor= 5.143) 8. Kang-Yi Lien, Chien-Ju Liu, Yi-Chien Lin, Pao-Lin Kuo and Gwo-Bin Lee “Extraction of genomic DNA and detection of single nucleotide polymorphism genotyping utilizing an integrated magnetic bead-based microfluidic platform,” Microfluidics and Nanofluidics, 6, 539–555, 2009. (SCI; Impact factor= 3.314) 9. Chien-Ju Liu, Kang-Yi Lien, Ching-Yi Weng, Jyh-Wei Shin, Tsuey-Yu Chang and Gwo-Bin Lee, “Magnetic-bead-based Microfluidic System for Ribonucleic Acid Extraction and Reverse Transcription Processes,” Biomedical Microdevices, 11, 339–350, 2009. (SCI; Impact factor= 2.924) 10. Tsung-Min Hsieh, Ching-Hsing Luo, Jung-Hao Wang, Jr-Lung Lin, Kang-Yi Lien and Gwo-Bin Lee, “A Two-dimensional Self-compensated Micro Thermal Cycler for One-step Reverse Transcription Polymerase Chain Reaction,” Microfluidics and Nanofluidics, 6(6), 797-809, 2009. (SCI; Impact factor= 3.314) 11. Kang-Yi Lien, Szu-Hsien Lee, Tieh-Jung Tsai, Tzong-Yueh Chen and Gwo-Bin Lee, “A microfluidic-based system using reverse transcription polymerase chain reactions for rapid detection of aquaculture diseases,” Microfluidics and Nanofluidics, 7, 795-806, 2009. (SCI; Impact factor= 3.314) 12. Kang-Yi Lien, Chien-Ju Liu, Pao-Lin Kuo and Gwo-Bin Lee, “Microfluidic system for rapid detection of α-thalassemia-1 deletion using saliva samples,” Analytical Chemistry, 81(11), 4502-4509, 2009. (SCI; Impact factor= 5.712) 13. Yu-Fang Lee, Kang-Yi Lien, Huan-Yao Lei and Gwo-Bin Lee “An integrated microfluidic system for rapid diagnosis of dengue virus infection,” Biosensors and Bioelectronics, 25, 745-752, 2009. (SCI; Impact factor= 5.143) 14. Kang-Yi Lien and Gwo-Bin Lee, “Miniaturization of molecular biological techniques for gene assay,” Analyst, Vol. 135, Issue 7, pp. 1499-1518, 2010. (SCI; Impact factor= 3.761) 15. Chen-Hsun Weng, Kang-Yi Lien, Sung-Yi Yang and Gwo-Bin Lee, “A suction-type, pneumatic microfluidic device for liquid transport and mixing,” in press, Microfluidics and Nanofluidics, DOI: 10.1007/s10404-010-0669-1, 2010 (SCI; Impact factor=3.286) 16. Kang-Yi Lien, Ying-Hsin Chuang, Lein-Yu Hung, Keng-Fu Hsu, Wu-Wei Lai, Chung-Liang Ho, Cheng-Yang Chou and Gwo-Bin Lee, “Rapid isolation and detection of cancer cells by utilizing integrated microfluidic systems,” in press, Lab on a Chip, 10(21), 2875-2886, 2010 (SCI; Impact factor=6.342). 17. Chih-Hung Wang, Kang-Yi Lien, Ting-Yu Wang, Tzong-Yueh Chen and Gwo-Bin Lee, “An integrated microfluidic loop-mediated-isothermal-amplification system for rapid sample pre-treatment and detection of viruses,” in press, Biosensors and Bioelectronics, DOI: 10.1016/j.bios.2010.08.083, 2010 (SCI; Impact factor=5.429). C. Conference Papers: 1. Jr-Lung Lin, Gwo-Bin Lee, Yi-Hsien Chang and Kang-Yi Lien, “Theoretical Prediction of Saturated Contact Angles in Electrowetting on Dielectric,” The 22nd National Conference on Mechanical Engineering(中國機械工程學會第二十二屆全國學術研討會), Taoyuan, Taiwan, Nov. 25-26, 2005. 2. Kang-Yi Lien, Wan-Chi Lee, Huan-Yao Lei, and Gwo-Bin Lee, “Integrated Micro Reverse Transcription Polymerase Chain Reaction Systems Using Super-paramagnetic beads for Virus Detection,” The 2nd International Meeting on Microsensors & Microsystems (IMμ2), Tainan, Taiwan, Jan. 15-18, 2006. 3. Kang-Yi Lien, Wan-Chi Lee, Huan-Yao Lei, and Gwo-Bin Lee, “Integrated Micro Reverse Transcription Polymerase Chain Reaction Systems Using Super-paramagnetic beads for Virus Detection,” The 1st IEEE-NEMS 2006, Zhuhai, China, Jan. 18-21, 2006. 4. Kang-Yi Lien, Cheng-Yu Liu, Jr-Lung Lin, Hao-Yu Tseng, Huan-Yao Lei, Huei-Huang Lee and Gwo-Bin Lee, “Microfluidic Systems Integrated with Pumping/Mixing and Separating Devices Using Magnetic Beads for Virus Detection,” The 4th Conference on Precision Machinery and Manufacturing Technology (第四屆精密機械與製造技術研討會), Kenting, Taiwan, May 26-28, 2006. 5. Kang-Yi Lien, Cheng-Yu Liu, Jr-Lung Lin, Hao-Yu Tseng, Wan-Chi Lee, Huan-Yao Lei and Gwo-Bin Lee, “Microfluidic Systems Integrated with Pumping/Mixing and Separation Devices for Virus Detection,” The 10th International Conference on Miniaturized Systems for Chemistry and Life Sciences (μ-TAS 2006), Tokyo, Japan, Nov. 5-9, 2006. 6. Kang-Yi Lien, Wang-Ying Lin, Chih-Hao Wang, Huan-Yao Lei and Gwo-Bin Lee, “Integrated Miniature RT-PCR Systems for Bio-sample Pretreatment and Detection,” The 10th Conference on Nano Engineering and Microsystem technology (第十屆奈米工程暨微系統技術研討會), Hsinchu, Taiwan, Nov. 30-Dec. 1, 2006. 7. Kang-Yi Lien, Jr-Lung Lin, Cheng-Yu Liu, Huan-Yao Lei and Gwo-Bin Lee, “Microfluidic Systems Integrated with Pumping/Mixing and Separation Devices Utilizing Magnetic Beads for Rapid Virus Detection,” The 30th National Conference on Theoretical and Applied Mechanics (中華民國力學學會第三十屆全國力學會議), Changhwa, Taiwan, Dec. 15-16, 2006. 8. Kang-Yi Lien, Wang-Ying Lin, Chih-Hao Wang, Huan-Yao Lei and Gwo-Bin Lee, “Miniature RT-PCR Systems Integrated with a Sample Pretreatment Device for Virus Detection,” The 20th IEEE International Conference on Micro Electro Mechanical Systems (MEMS 07), Kobe, Japan, Jan. 21-25, 2007. 9. Sung-Yi Yang, Kang-Yi Lien, Kao-Jean Huang, Huan-Yao Lei and Gwo-Bin Lee, “Immunoassay Utilizing Magnetic Beads for Rapid Virus detection in the Microfluidic Flow Cytometer System,” The 11th International Conference on Miniaturized Systems for Chemistry and Life Sciences (μ-TAS 2007), Paris, France, Oct. 7-11, 2007. 10. Kang-Yi Lien, Chien-Ju Liu, Jyh-Wei Shin, Tsuey-Yu Chang and Gwo-Bin Lee, “Bead-Based Miniature Microfluidic Systems for Rapid RNA Extraction And Reverse Transcription,” ASME Micro/Nanoscale Heat Transfer International Conference (MNHT 08), Tainan, Taiwan, Jan. 6-9, 2008. 11. Kang-Yi Lien, Chien-Ju Liu and Gwo-Bin Lee, “Magnetic-bead-based Microfluidic Systems for Detection of Genetic Diseases,” The 21st IEEE International Conference on Micro Electro Mechanical Systems (MEMS 08), Tucson, Arizona, USA, Jan. 13-17, 2008. 12. Sung-Yi Yang, Kang-Yi Lien, Kao-Jean Huang, Huan-Yao Lei and Gwo-Bin Lee, “Immunoassay Utilizing Magnetic Beads-based Microfluidic system for Rapid Virus detection,” The 25th National Conference on Mechanical Engineering(中國機械工程學會第二十五屆全國學術研討會), Changhua, Taiwan, Nov. 21-22, 2008. 13. Kang-Yi Lien, Chien-Ju Liu, Pao-Lin Kuo and Gwo-Bin Lee, “Bead-based Microfluidic Platform Integrated with Optical Detection Devices for Rapid Detection of Genetic Deletion from Saliva,” The 22nd IEEE International Conference on Micro Electro Mechanical Systems (MEMS 09), Sorrento, Italy, Jan. 25-29, 2009. 14. Yu-Fang Lee, Kang-Yi Lien, Huan-Yao Lei and Gwo-Bin Lee, “A Magnetic-Bead Based Microfludic System for Rapid Detection of Immunoglobulins,” The 15th International Conference on Solid-State Sensors, Actuators and Microsystems (Transducer 09), Denver, Colorado, USA, Jun. 21-25, 2009. 15. Yu-Fang Lee, Kang-Yi Lien, Huan-Yao Lei, Ruo-Chi Hsu and Gwo-Bin Lee, “An Immunomagnetic-bead-based Microfluidic System for Rapid Diagnosis of Influenza Infection,” The 5th International Conference on Nano/Micro Engineered and Molecular Systems (IEEE-NEMS 2010), Xiamen, China, Jan. 20-23, 2010. 16. Chen-Yi Lee, Song-Bin Huang, Kang-Yi Lien, Gwo-Bin Lee, Ming-Yang Lin, “Tunable Magnetic Alginate Microspheres by Using a Microfluidic Device,” The 5th International Conference on Nano/Micro Engineered and Molecular Systems (IEEE-NEMS 2010), Xiamen, China, Jan. 20-23, 2010. 17. Kang-Yi Lien, Chien-Ju Liu, Keng-Fu Hsu, Cheng-Yang Chou and Gwo-Bin Lee, “A Magnetic Bead-based 3D Microfluidic Incubator for Rapid Purification and Detection of Tumor Cells,” The 23rd IEEE International Conference on Micro Electro Mechanical Systems (MEMS 10), Hong Kong, China, Jan. 24-28, 2010. 18. Johannes Piepenbrock, Artur Scholz, Gwo-Bin Lee, Chih-Hung Wang, Kang-Yi Lien, Jyh-Ching Juang, Jiun-Jih Miau, Bernd Dachwald, “Bio-Lab - Case Study of a Biological Experiment for CubeSat Missions,” Small Satellites Systems and Services-The 4S Symposium 2010, Madeira, Portugal, May 31-June 4, 2010. 19. Chih-Hung Wang, Kang-Yi Lien, Ting-Yu Wang, Tzong-Yueh Chen and Gwo-Bin Lee, “Integrated Microfluidic Loop-mediated-isothermal-amplification System for Rapid Diagnosis of Aquaculture Virus,” The 14th International Conference on Miniaturized Systems for Chemistry and Life Sciences (μ-TAS 2010), Groningen, The Netherlands, Oct. 3-7, 2010. 20. Kang-Yi Lien, Lien-Yu Hung, Huan-Yao Lei and Gwo-Bin Lee, “A Magnetic-bead-based Immunoassay for Rapid Purification and Detection of Influenza Viruses Utilizing Suction-type Microfluidic Systems,” The 14th International Conference on Miniaturized Systems for Chemistry and Life Sciences (μ-TAS 2010), Groningen, The Netherlands, Oct. 3-7, 2010. D. Book 1. Kang-Yi Lien, “Miniature Microfluidic System Integrated with a Sample Pretreatment Device for Rapid Nucleic Acid Amplification,” M. S. thesis, NCKU, 2007. 2. Kang-Yi Lien, Huan-Yao Lei and Gwo-Bin Lee, “Dengue detection chips,” Invited chapter of Dengue Disease (ISBN:978-81-308-0290-9), Research Signpost Publisher, India, pp. 87-104, 2008 3. Kang-Yi Lien, “Integrated microfluidic systems for the detection of cancer, infectious and genetic diseases,” PhD dissertation, National Cheng Kung University, 2010. E. Other Publications 1. Kang-Yi Lien, Wan-Chi Lee, Huan-Yao Lei and Gwo-Bin Lee, “Integrated Reverse Transcription Polymerase Chain Reaction Systems for Virus Detection,” BANYAN-Research Express@NCKU, Volume 1(5), 2007.
題目 微流體晶片系統應用於臨床診斷與分析
共同指導生 原先的老師