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姓名 張文馨
年級 已畢業學長
組別 丙組、動植物病原微生物快速篩選
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學歷
    台灣大學農業化學系學士 台灣大學生物化學及分子生物學研究所碩士
經歷
    台灣大學生物化學及分子生物學研究所助教 台灣大學藥學系助教 華鼎生技顧問股份有限公司法規專員 成功大學工程科學系研究助理 清華大學動力機械工程系研究助理
專長及研究領域
榮譽及獎勵
    清華大學動力機械系101年度獎助金 清華大學100年度校長獎學金 1) Journal papers: 1. Wen-Hsin Chang, Sung-Yi Yang, Chih-Lin Lin, Chih-Hung Wang, Ping-Chen Li; Tzong-Yueh Chen, Fuh-Jyh Jan, Gwo-Bin Lee (2013) “Detection of viruses directly from the fresh leaves of a Phalaenopsis orchid using a microfluidic system.” Nanomedicine: Nanotechnology, Biology, and Medicine (SCI Impact factor: 6.692), Ranking: 11/112=9.8% (MEDICINE, RESEARCH & EXPERIMENTAL), Accepted. 2. Chen-Min Chang, Wen-Hsin Chang, Chih-Hung Wang, Jung-Hao Wang, John D. Mai and Gwo-Bin Lee (2013) “Nucleic acid amplification using microfluidic systems.” Lab on a Chip, 13: 1225-1242 (SCI Impact factor: 5.670), Ranking: 6/72=8.3% (BIOCHEMICAL RESEARCH METHODS) 3. Wen-Hsin Chang, Sung-Yi Yang, Chih-Hung Wang, Ming-An Tsa, Pei-Chyi Wang, Tzong-Yeh Chen, Shih-Chu Chen, Gwo-Bin Lee (2013) “Rapid isolation and detection of aquaculture pathogens in an integrated microfluidic system using loop-mediated isothermal amplification.” Sensors and Actuators B: Chemistry, 180: 96-106, (SCI Impact factor: 3.898), Ranking: 3/58=5.2% (INSTRUMENTS & INSTRUMENTATION) 4. Sai-Wen Tang, Tsung-Cheng Yang, Wei-Chou Lin, Wen-Hsin Chang, Chung-Chieh Wang, Ming-Kuen Lai and Jung-Yaw Lin (2011) "Nicotinamide N-methyltransferase induces cellular invasion through activating matrix metalloproteinase-2 expression in clear cell renal cell carcinoma cells." Carcinogenesis, 32: 138-45 (SCI Impact factor: 5.702), Ranking: 24/196=12.2% (ONCOLOGY) 5. Sai-Wen Tang, Wen-Hsin Chang, Yih-Ching Su, Yu-Chi Chen, Yen-Han Lai, Pei-Tzu Wua, Chyong-Ing Hsu, Wei-Chou Lin, Ming-Kuen Lai, and Jung-Yaw Lin (2009) "MYC pathway is activated in clear cell renal cell carcinoma and essential for proliferation of clear cell renal cell carcinoma cells." Cancer Letters, 273: 35-43 (SCI Impact factor: 4.238), Ranking: 43/196=21.92% (ONCOLOGY) 6. Sai-Wen Tang, Wen-Hsin Chang, Yu-Wei Chao, Chung-Yei Lin, Hsiao-Fen Chen, Yen-Han Lai, Bo-Wen Zhan, Yih-Ching Su, Sen-Wen Jane, Yu-Chi Chen, Chyong-Ing Hsu, Wei-Chou Lin, Kao-Chung Wang, Ming-Kuen Lai and Jung-Yaw Lin (2006) "Identification of Differentially Expressed Genes in Clear Cell Renal Carcinoma by Analysis of Full-length cDNA Library." Journal of Biomedical Science, 13: 233-40 (SCI Impact factor: 1.980), Ranking: 63/112=56.2% (MEDICINE, RESEARCH & EXPERIMENTAL) 7. Chia-Chu Tsai, Yi-Da Chung, Hong-Jen Lee, Wen-Hsin Chang, Yutaka Suzuku, Sumio Sugano, Jung-Yaw Lin (2003) “Large-Scale Sequencing Analysis of the Full-Length cDNA Library of Human Hepatocellular Carcinoma." Journal of Biomedical Science, 10: 636-43 (SCI Impact factor: 1.980), Ranking: 63/112=56.2% (MEDICINE, RESEARCH & EXPERIMENTAL) 2) Conference papers: 1.Wen-Hsin Chang, Chih-Hung Wang, Sung-Yi Yang, Yi-Cheng Lin, Jiunn-Jong Wu, Mel S Lee and Gwo-Bin Lee "AN INTEGRATED MICROFLUIDIC SYSTEM FOR RAPID ISOLATION AND DETECTION OF LIVE BACTERIA IN PERIPROSTHETIC JOINT INFECTIONS" (The 27th IEEE International Conference on Micro Electro Mechanical Systems; MEMS 2014, San Francisco, USA) 2. Chih-Lin Lin, Wen-Hsin Chang, Chih-Hung Wang, Ping-Chen Li, Fuh-Jyh Jan, Tzong-Yueh Chen and Gwo-Bin Lee “AN INTEGRATED MICROFLUIDIC SYSTEM USING BURIED OPTICAL FIBERS FOR DETECTION OF PHALAENOPSIS ORCHID PATHOGENS” (The 17th International Conference on Solid-State Sensors, Actuators and Microsystems; TRANSDUCERS 2013, Barcelona, Spain) 3. Wen-Hsin Chang, Jung-Hao Wang, Wei-Shuo Ling, Lie Cheng, Chih-Hung Wang, Shainn-Wei Wang, and Gwo-Bin Lee. “An Intergated Microfluidic System for Detecting Human Immunodeficiency Virus in Blood Samples” (The 26th IEEE International Conference on Micro Electro Mechanical Systems; MEMS 2013, Taipei, Taiwan) 4. Wen-Hsin Chang, Sung-Yi Yang, Chih-Hung Wang, Tzong-Yeh Chen, Ping-Chen Li, Fuh-Jyh Jan, and Gwo-Bin Lee. “Pathogen Detection from Phalaenopsis Orchids by Using an Integrated Microfluidic System” (The 6th IEEE International Conference on Nano/Molecular Medicine and Engineering; NANOMED 2012, Bangkok, Thailand) 5. Yi-Chih Su, Chih-Hung Wang, Wen-Hsin Chang, Long-Huw Lee, and Gwo-Bin Lee. “Multiple pathogen detections for poultry by using an integrated microfluidic system” (The 16th International Conference on Miniaturized Systems for Chemistry and Life Science; microTAS 2012, Okinawa, Japan) 6. Wen-Hsin Chang, Sung-Yi Yang, Chih-Hung Wang, Ming-An Tsai, Pei-Chyi Wang, Shih-Chu Chen, Ping-Chen Li, Fuh-Jyh Jan, Tzong-Yeh Chen and Gwo-Bin Lee. “Development of integrated microfluidic platform for agricultural pathogen survellience and quarantine” (The 2nd Symposium on Engineering Medicine and Biology Applications & International Workshop on Bio-inspired Systems and Prosthetic Devices; SEMBA/BIOPRO 2012, Taichung, Taiwan) 7. Wen-Hsin Chang, Sung-Yi Yang, Chih-Hung Wang, Ming-An Tsai, Pei-Chyi Wang, Shih-Chu Chen, Tzong-Yueh Chen and Gwo-Bin Lee. "Integrated Microfludic Loop Mediated Isothermal Am plication System for Rapid Isolation and Detection of Aquarium Fish Pathogens in one single step” (The 16th International Conference on Solid-State Sensors, Actuators and Microsystems; TRANSDUCERS 2011)
專利
    1. “檢測魚類病原之引子組、方法及套組” 李國賓、陳石柱、陳宗嶽、張文馨、王志宏、蔡明安, filing date: 2011/12/12 with a filing number 100145819. 2. “檢測動物或植物病原之引子組、方法及套組” 李國賓、張文馨、王志宏、陳宗嶽、王廷瑜、李龍湖、楊佳玲、王惠亮、王怡瑾、莊智傑、詹富智、李品臻, filing date: 2012/07/23 with a filing number 101126506. US patents: 1. "PRIMER SET,METHOD AND KIT FOR DETECTING PATHOGEN IN FISH"(US2288), Gwo-Bin Lee, Shih-Chu Chen, Tzong-Yueh Chen, Wen-Hsin Chang, Chih-Hung Wang and Ming-An Tsai, and filed on: 3 December 2012, Appln. No.: 13/692, 210. 2. "PRIMER SET, METHOD AND KIT FOR DETECTING PATHOGEN IN ANIMALS OR PLANTS"(US2669), Gwo-Bin Lee, Wen-Hsin Chang, Chih-Hung Wang, Tzong-Yueh Chen, Ting-Yu Wang, Long-Huw Lee, Jia-Ling Yang, Hui-Liang Wang, I-Chin Wang, Chih-Chieh Chuang, Fuh-Jyh Jan, Ping-Chen Li, and filed on: 13 Mar 2013, Appln. No.: 13/785,734.
題目 微流體系統於動植物檢疫之應用
共同指導生 原先的老師